The expansion of a trinucleotide repeat (TNR) region of DNA is currently associated with over 40 known neurodegenerative and neuromuscular disorders. The focus of the …
Towards the full understanding the physiology of human Sigma-1 receptor (Sig-1R), we developed a novel ligand-based enrichment strategy and mass spectrometry analysis of the receptor. …
Recombinant NANS module 2, with DEBS TE appended to the C-terminus, was expressed in Escherichia coli BAP1. Incubation of NANS module 2+DEBS_TE with (2RS) 2 …
Our central goal in this thesis is to investigate the vibrational energy relaxation (VER) of perylene in solution. The size of a perylene molecule makes …
Poly (lactic-co-glycolic acid) (PLGA) has been widely used as a biomaterial in regenerative medicine due to its good biocompatibility and biodegradability properties. Moreover, nanotopographies have …
Nanoparticles (NPs) in 1 to10 nm diameter range have been investigated extensively for their enhanced catalysis of myriad electrocatalytic reactions. Past studies have consistently indicated …
Myelin is a compact multilayer membrane, which is spirally wound around the nerve axons to protect the action potential being transported along the axons from …
Bis arene ruthenium complexes have the ruthenium metal center bonded to the aromatic rings in a π-manner. They have a unique structure with easily functionalized …
Multicomponent nanoparticles (NPs) with at least two different components in one nanostructure have attracted great interest due to the multifunctionalities and enhanced properties they exhibit. …
An oxidized lesion of guanine that is detected following exposure of DNA to several oxidizing agents is 8-oxo-7,8-dihydro-guanine (8-oxoG). Studies done in vitro show that …
Understanding of structural, reaction and charge transfer dynamics of any molecular system has been a challenge for both modern spectroscopists and theorists. The structural changes …
