Variation in genomes occurs in many forms, from single nucleotide changes to gains and losses of entire chromosomes. Large-scale rearrangements, called structural variants (SVs), are …
Cancer is a disease resulting from genomic mutations that occur during an individual's lifetime and cause the uncontrolled growth of a collection of cells into …
Cancer is an evolutionary process where cells acquire somatic mutations over time. As a result of this process, tumors are often highly heterogeneous — containing …