This dissertation is motivated by complex data architectures—typical in genetics research—that break the assumptions of classical frequentist analyses. Predictors are not necessarily independent nor fewer …
Neurogenesis in the mammalian hippocampus persists throughout adulthood, but the function of newly-born hippocampal cells remains largely unknown. This dissertation investigates the effects of neurogenesis …
Terahertz scattering scanning near field optical microscopy (THz s-SNOM) has become an active research topic for its effectiveness in characterizing electronic behavior in many materials …
The development of high-throughput sequencing technology enables a deeper understanding of gene regulatory mechanisms by performing statistical analyses of genomic data. Most traditional statistical approaches …
Transgenic neuromodulation tools (i.e., optogenetics and chemogenetics) enable the manipulation of brain activity using targeted genetic delivery strategies for transducing specific cells to produce transgenic …
In this dissertation, I argue that the novel was the laboratory in which emerging theories of embodied cognition developed sensible forms for nineteenth-century American audiences. …
Structural integrity is essential for critical load bearing structures such as pipelines. Accurate characterization of hidden flaws, theoretical modeling of structural materials, and novel computational …
Approximately half of magnetic resonance imaging (MRI) procedures require intravenously administered contrast agents image enhancement and greater diagnostic precision. The current clinical standard for MRI …
Background The Fundamental Social Cause of Disease Theory explains how power and distribution of resources affect health outcomes. While socioeconomic position (SEP) and racism have …
Liver transplantation remains the standard of care for liver failure but is constrained by a shortage of organs. Fetal hepatic cell transplantation (HCT) offers a …
As anthropogenic carbon emissions continue to drive atmospheric CO2 concentration higher, global climate models are needed to predict how the Earth system will respond to …
Presently, fibrosis and polyploidal giant cancer cells (PGCCs) have links to tumor onset and progression that are poorly understood; however, disentangling this is vital to …
Age is a fundamental aspect of biology that underlies the efficacy of a broad range of functions. Identifying determinants for how quickly or slowly we …
Abstract of (Cell death associated with ENDS vapor exposure), by (Valeriia Syrovatska), ScM, Brown University, January 2023 The use of electronic nicotine delivery systems (ENDS) …
Diffusion Monte Carlo (DMC) is one of the most accurate techniques available for calculating the electronic properties of molecules and materials, yet it often remains …
The neuromuscular junction (NMJ) is required for muscle excitation, and its dysfunction is thought to contribute to deficits observed in sarcopenia and neuromuscular disease. The …
Abstract of “Claiming Anjelamaría Dávila: Black Women’s Imaginings of Decolonization in Puerto Rico” by Katsí Yarí Rodríguez Velázquez, Ph.D., Brown University, February 2023 This dissertation …
Abstract of “A Life-Course Approach to Gender Differences in Work Outcomes and Occupational Mobility in Mexico: The Role of Migration” by Anairis Hernández Jabalera, Ph.D., …
One of the major consequences of aging is the loss of voluntary motor capacity, which reduces the self-sufficiency and overall health of individuals. Among the …
