Atherosclerotic plaque calcification is associated increased risk of cardiovascular events. Inflammation plays a key role in the development of atherosclerosis and is thought to potentially …
This thesis is divided into two parts. The first part of this thesis, including chapters 1-3, examines the role of the protein Muscle specific kinase …
Specification of the germline, the cells which give rise to eggs and sperm, is essential for sexually reproducing organisms. The mechanism by which animals specify …
Strict regulatory mechanisms ensure that the cell’s genome is perfectly duplicated. In eukaryotic cells, origins of replication fire once and only once per cell cycle. …
Defining diverse roles of a single transcription factor on the cellular level is key to understanding its role in the context of an organism. However, …
Abstract of “GA-Binding Proteins Regulate Dosage Compensation in Drosophila melanogaster” by Emily Grace Kaye, Ph.D., Brown University, May 2018 A transcription factor (TF) will bind …
Resistance to starvation is a classical complex trait, where varying genetic and environmental landscapes can greatly modify an animal’s ability to cope. In this study, …
Germ cell specification is required for reproduction in all sexually reproducing animals. During animal development, animals can specify their germ cells through inheritance of maternal …
Mitochondria are referred to as the “powerhouse of the cell” for their ability to perform oxidative phosphorylation (OXPHOS), but they also perform a diverse array …