In this thesis we provide evidence that the FAIRE method can reveal interesting and relevant changes in genome-wide chromatin organization as cells undergo replicative senescence, …
We present an intuitive strategy for predicting the effect of sequence variation on splicing. In contrast to transcriptional elements, splicing elements appear to be strongly …
Fluorescence in situ hybridization (FISH) is a molecular labeling technique that can be used to visualize and taxonomically identify microbial cells. In this study, spectral …