The specificity and extent of RNA editing by ADAR enzymes is determined largely by local primary sequence and secondary structural imperfections in duplex RNA. Here, …
Cytoplasmic mRNA localization is understood as an important biological strategy for establishing cell and developmental polarity in a variety of organisms and cell types. In …
Substitutions that disrupt pre-mRNA splicing are a common cause of genetic disease. On average, 13.4% of all hereditary disease alleles are classified as splicing mutations …
RNA localization in Xenopus laevis oocytes is facilitated by the formation of specific cytoplasmic ribonucleoprotein (RNP) granules termed L-bodies. RNP granules, also known as biomolecular …
Transposable elements (TEs) are parasitic mobile sequences of DNA that proliferate throughout host genomes by replicating and reinserting themselves into new regions of DNA. This …