Antimicrobial resistance poses a global challenge to human health that is only expected to increase without significant treatment innovations. Novel therapeutic strategies are needed for …
Fungal infections present a significant and evolving threat to human health. The SARS-COV-2 pandemic demonstrated how human fungal pathogens can target immunocompromised individuals, resulting in …
The gut microbiome is essential for the maintenance of host health, and perturbations to the gut microbial community can lead to disease states. While antibiotics …
The human microbiome contributes to a number of physiological processes, including digestion, neurological development, and proper immune function. Due to its central role in human …
Natural selection causes genetic variants that increase fitness to spread within a population. Individuals bearing such alleles will leave behind more descendants and those descendants …
The rise in antibiotic resistance and the importance of the mammalian microbiome necessitates new models that could expedite and streamline the study of host-microbiome interactions …
Candida albicans is a normal commensal of the human host but also a frequent cause of mucosal and systemic fungal infections. This species commonly colonizes …
Candida albicans is a commensal fungus that colonizes the human gastrointestinal tract without causing disease. However, C. albicans is also an opportunistic pathogen that can …
The gut microbiome is the assemblage of symbiotic microbes inhabiting distinct ecological niches within the host that participate in key physiological functions such as energy …
Antibiotic therapy alters bacterial abundance and metabolism in the gut microbiome, leading to adverse health outcomes such as dysbiosis and opportunistic infections. Additionally, antibiotic effectiveness …
Schistosomiasis is a neglected tropical disease intimately associated with poverty, which afflicts over 250 million people world-wide and leads to significant morbidity in endemic regions. …
The human body is home to over one trillion microbes, more than the total number of human cells (1). Despite having been relatively understudied until …
Objective This research examines the alterations and potential resultant consequences of tobacco smoking on the human microbiome. Background Tobacco smoking is a risk factor for …
