Background: Home to around 7.7 million HIV positive individuals, South Africa holds 20% of the global HIV population. HIV presents many challenges, such as stigmatization, …
A social-contextual approach to health promotion includes exploration of the influence of faith leaders and religious communities in health behaviors and outcomes. This thesis reports …
Objective: The objective of this thesis was to establish an experimental 3D culture system based on liver cancer (HepG2) cells in a gelatin scaffold and …
Abstract of A Bioengineering Approach to Develop New Technologies for Genomics-Based Healthcare, by Olivia Ott, Sc.M. Brown University, May 2023. Genomics-based healthcare is a rapidly …
Morphogen activity gradients assign positional information within fields of cells in a concentration-dependent manner. As transcriptional changes respond to signaling activity thresholds, cells must encounter …
Objective: Cervical cancer causes 311,000 deaths annually. However, routine pap smears can facilitate early detection and improve patient outcomes. Liquid Pap smears are conducted in …
There has been mounting concern over the health hazards of per- and polyfluoroalkyl substances (PFAS), which has spread beyond the scientific community to federal regulators, …
Study Objective: Tranexamic Acid (TXA), an anti-fibrinolytic, has been used in military trauma cases and civilian Emergency Departments for several years. This study aims to …
Prokaryotic microbes, commonly termed bacteria, are essential components of the ecosystem in the open ocean. They are major primary producers, major diazotrophs that fix dinitrogen …
This thesis explores clinical and social factors to characterize underweight malnutrition on the national and global level using the UNICEF Childhood Malnutrition Datasets (survey-level data …
Agitation is a symptom of restlessness and overt behavior in individuals due to a variety of psychological, psychiatric, and medical conditions. The symptoms are seen …
Persons afflicted with neuromuscular diseases, whether acute or congenital, frequently suffer from secondary musculoskeletal conditions. These conditions may be so severe that they prevent persons …
Recent increases in the incidence of congenital (hypospadias, cryptorchidism) and adult-onset (testis germ cell cancer, lowered sperm counts) diseases of the male reproductive tract are …
Background: Predictive analytic models, including machine learning (ML) models, are increasingly integrated into electronic health record (EHR)-based decision support tools for clinicians. These models have …
Atherosclerotic plaque calcification is associated increased risk of cardiovascular events. Inflammation plays a key role in the development of atherosclerosis and is thought to potentially …
The sigma-2 receptor is a pharmacologically-defined protein receptor present in a variety of tissues, and interest in its role in a wide array of diseases …
Cytokinesis is an essential process for the proliferation of eukaryotic species. However, our knowledge of how a eukaryotic cell accomplishes cytokinesis is relegated to a …
The goal of this study is to create a simulation-trained convolutional neural network (CNN) that can detect and characterize stiffer tissue embedded in a softer …
Antibiotic resistance is an urgent threat to public health. For this reason, new antimicrobial therapies are constantly needed to treat ever-evolving pathogens. One such pathogen …
