Automation has been rapidly changing the research performed in the scientific community. With more high-throughput technologies available to both academic and industrial scientists, improvements to …
All disciplines of biomedical research utilize in vitro models to answer a range of biological questions. Traditional in vitro models, two-dimensional (2D) cell monolayers, fail …
Microplastic pollution of marine environments is a pressing problem for the health of aquatic ecosystems and for global food supply. Many studies have been done …
Subcellular mRNA localization is a conserved mechanism across eukaryotes, which is found in both somatic and germ cells. RNA localization in combination with local translation …
The mammalian opsin family of light-sensitive G protein-coupled receptors (GPCRs) includes retinal pigments like rhodopsin (OPN2) and cone opsins (OPN1), which mediate vision, as well …
Pollution, the release of chemicals into the environment, is the result of current and historic industrial and waste management practices and a range of human …
Germ cell specification is required for reproduction in all sexually reproducing animals. During animal development, animals can specify their germ cells through inheritance of maternal …
Substitutions that disrupt pre-mRNA splicing are a common cause of genetic disease. On average, 13.4% of all hereditary disease alleles are classified as splicing mutations …
The human genome is organized in a hierarchical manner from higher order to lower order structures. At the highest level are chromosome territories that are …
The protein ser/thr phosphatases (PSPs) dephosphorylate over 2000 of key biological targets, making them attractive therapeutic targets. The serine/threonine protein phosphatases 1 and 2B (PP1; …
Aging is the main contributing factor when it comes to the development of neurological diseases. Astrocytes in the subventricular zone (SVZ) play an important role …
JC polyomavirus (JCPyV) is a small non-enveloped virus that establishes lifelong, persistent infections in the majority of the adult population. Immune-competent patients are generally asymptomatic, …
As the release of novel chemicals into the environment outpaces the ability to perform exhaustive toxicological assessments, there is growing concern about the effects of …