Objective: The objective of this thesis was to establish an experimental 3D culture system based on liver cancer (HepG2) cells in a gelatin scaffold and …
This thesis explores clinical and social factors to characterize underweight malnutrition on the national and global level using the UNICEF Childhood Malnutrition Datasets (survey-level data …
In this thesis, the potential success of a novel drug delivery system (PDAL DDS) in the current antifungal DDS market was evaluated. Focus was placed …
Central nervous system disease pathologies are poorly understood in part due to the inability of animal and in vitro models to recapitulate their complexity. It …
Penicillin Binding Protein 5 (PBP5) is a membrane bound transpeptidase that plays an important role in β-lactam antibiotic resistance in Enterococcus faecium. Normally, β-lactams inhibit …
Meniscus tears are among the most frequent orthopaedic injuries that commonly affect active and young populations. These tears ultimately increase the risk of developing post-traumatic …
Abstract of (Cell death associated with ENDS vapor exposure), by (Valeriia Syrovatska), ScM, Brown University, January 2023 The use of electronic nicotine delivery systems (ENDS) …
Characterizing the morphology of the carpometacarpal (CMC) joint and how it changes with osteoarthritis progression is important for understanding the pathoetiology of this multifactorial disease. …
Abstract of Characterization of Temperature-Pressure Induced Morphology in High Molecular Weight Poly (Ethylene Oxide) by Sheila Velagapudi, ScM., Brown University, May 2020 The focus of …
Various mixtures of melanins are responsible for determining our skin, eyes, and hair color for protection from UVR. Research has shown impaired melanin synthesis, storage …
Abstract of CHARACTERIZING SEEDING DENSITY AS A MECHANISM OF CHEMOTHERAPY RESISTANCE IN CANCER CELLS, by Ujwal Punyamurtula, ScM, Brown University, May, 2022. While the 50% …
Background- Angelman syndrome (AS) is a severe cognitive disorder caused by loss of neuronal expression of the E3 ubiquitin ligase UBE3A. Brain-derived neurotrophic factor (BDNF) …
Polymeric nanoparticles loaded with insulin is a highly sought-after drug delivery system in the treatment of diabetes mellitus. The goal of this experiment is to …
Infectious disease is one of the most severe healthcare issues worldwide (Nathan, 2004; Nathan & Goldberg, 2005; WHO, 2002). Moreover, this healthcare issue is worsened …
The relationship between alcohol use disorder (AUD) and disrupted circadian rhythms is likely bidirectional. However, prior research has focused more extensively on how alcohol use …
Abstract of “Enhancing Suicidal Behavior Comorbidity Knowledge Through Data Mining Based on Genetic Associations”, By Claudia Knox Jones, ScM, Brown University, May 2019. There is …
Hepatitis B virus (HBV) is one of the hepadnaviridae family members that causes acute and chronic hepatitis. So far, there is no effective treatment for …