Despite many studies linking FOXO factors to longevity, how these factors directly regulate aging particularly in humans, is not completely understood. The focus of this …
Defining diverse roles of a single transcription factor on the cellular level is key to understanding its role in the context of an organism. However, …
Abstract of “GA-Binding Proteins Regulate Dosage Compensation in Drosophila melanogaster” by Emily Grace Kaye, Ph.D., Brown University, May 2018 A transcription factor (TF) will bind …
The transcriptional repressor Rev-erbα is known to attenuate gene expression in a variety of metabolic pathways including gluconeogenesis and fatty acid metabolism. Changes in these …
The opportunistic fungal pathogen Candida albicans is capable of colonizing diverse host niches throughout the human body. The ability of C. albicans to undergo a …
Dosage compensation in Drosophila is a valuable model for studying how transcription complexes are targeted throughout the genome because all of the genes along the …