Bone anchored prosthetic attachments, like other percutaneous devices, suffer from poor soft tissue integration, seen as chronic inflammation, infection, epithelial downgrowth and regression. We looked …
Traumatic injury to the spinal cord often results in irreversible loss of function as the central nervous system fails to spontaneously regenerate. The application of …
Trypanosomes are the causative agent of human African sleeping sickness and nagana in cattle. The bovine parasite, Trypanosoma brucei brucei (T. b. brucei), is unable …
This dissertation discusses two related clinical applications of visible regime diffuse reflectance spectroscopy as well as two new configurations of liquid crystal microspectrometer suitable in …
I investigated factors that influence microbial diversity and composition and the consequences of this diversity for plant communities. First, I used cloning and sequencing of …
Background: Although depression is prevalent among working-aged Medicaid enrollees with physical disabilities, the association of depression and health service utilization has not been examined in …
Desirable cytocompatibility properties of nano-sized ceramics were combined with the tunable degradability and deformability of a select polymer (poly-lactide-co-glycolide, or PLGA) to optimize biological and …
Titanium, titanium alloys, and cobalt-chromium alloys are widely used in orthopedic applications. To promote the osseointegration of implants into juxtaposed bone, an electrochemical surface modification …
Mucoadhesion is defined as the adhesion between a biomaterial and mucus. Mucoadhesion enhances drug delivery by increasing transit time and causing intimate contact with intestinal …
The method of phase inversion nanoencapsulation was utilized to develop an oral insulin microsphere delivery system fabricated from poly(fumaric-co-sebacic anhydride) (p(FASA)). As particle uptake in …
It is widely assumed that differences in wing morphology among bat species are reflected by interspecific differences in flight performance, and consequently, in the way …
Oral absorption of many potential pharmaceuticals is limited due to problems of enzyme degradation, dissolution and permeation. Bioadhesive poly(fumaric-co-sebacic) anhydride microspheres have been investigated as …
My graduate work examined the reaction of neuronal cells to the shape of their extra-cellular environment. Over the last century, many studies have confirmed that …
This doctoral work is mainly motivated by statistical challenges emerging from personalized medicine in the context of care for cancer patients. We propose methodology to …
Prions are unique proteins that can exist in multiple states. In the prion form these proteins self-replicate, directing other like molecules to adopt the prion …
Little recent research exists identifying home health agency (HHA) organizational and market characteristics that influence home health quality. This study, grounded in organizational sociology, had …