Prokaryotic microbes, commonly termed bacteria, are essential components of the ecosystem in the open ocean. They are major primary producers, major diazotrophs that fix dinitrogen …
Head and neck squamous cell carcinomas form a heterogeneous group of cancers of the upper aerodigestive tract, arising from the surface epithelium of the oral …
In this thesis,alpha-bungarotoxin (Bgtx) was validated as a tool for exploring the function and regulation of three otherwise Bgtx-insensitive ion channels: the first is a …
This thesis work is motivated by the specific challenges in analyzing data from clinical trials in behavioral medicine. Specifically, smoking cessation and physical activity trials. …
While current antibiotic agents provide suitable and cost effective means of inhibiting bacterial infiltration of biomedical devices, they are slowly becoming obsolete as microbial species …
Today bone defects such as bone fractures, osteoporosis or bone cancers represent a common and significant clinical problem. However, traditional micron size implant materials have …
A detailed understanding of ribosomal RNA (rRNA) structure is essential to understanding its function in the cell. Here we present a new comparative phylogenetic analysis …
Malignant mesothelioma is an aggressive cancer of the mesothelial lining causally linked to asbestos exposure and is highly resistant to current therapies. We hypothesize a …
This dissertation describes translational research conducted to develop a rapid diagnostic for the detection of endotoxin using liquid crystal sensor technology. Due to the elastic …
Overweight, obesity, weight gain, and weight cycling are associated with increased health risk. The purpose of this dissertation was to characterize weight trajectories during middle …