There is a high demand for developing a computational platform for global analysis of position- specific sequence variation within HIV-1 subtypes. Undesirable probe designs can …
All disciplines of biomedical research utilize in vitro models to answer a range of biological questions. Traditional in vitro models, two-dimensional (2D) cell monolayers, fail …
Adipose-derived stem cells (ASCs) represent a promising cell source for cell-based therapies and tissue engineering applications because of their multipotency and abundance. However, these cells …
Intravascular catheter related bloodstream infections are a leading cause of hospital-acquired nosocomial infections all over the world, which result in not only the burden of …
Subcellular mRNA localization is a conserved mechanism across eukaryotes, which is found in both somatic and germ cells. RNA localization in combination with local translation …
Cellular heterogeneity is inherent in the brain, and resolving differential cell type-specific contributions to overall function is critical for understanding both normal and pathological neurobiology. …
Insulin and IGF signaling (IIS) is a complex system that controls diverse processes including development, metabolism, stress responses and aging. Drosophila melanogaster IIS is propagated …
Recent machine learning techniques have become a powerful tool in a variety of tasks, including neural decoding. Artificial neural network models, particularly recurrent models, can …
This thesis details design and development of a novel neonatal transilluminator, focusing on the development of robust electronic circuitry and a testable prototype. Transilluminators are …
Pancreatic and colorectal cancer are highly aggressive and challenging to treat. Both cancers have low survival rates and there is a need for more elaborate …
As medical technologies advance, effective vertebrate models of human disease are vital to determine safety and efficacy of treatments. My research has further developed zebrafish …
The overarching goal of this project is to utilize modulated differential scanning calorimetry and hot-stage x-ray diffraction to characterize and quantify the formation of oriented …
Abstract of Disruption of yfjD Gene in Francisella, by Japheth Omonira, ScM., Brown University, May 2018. Francisella tularensis is the causative agent of tularemia, a …
The safe and economical disposal of electronic waste (E-waste) is a major issue worldwide, as consumption of electronics continues to rise with no end in …
Abstract of “Effects of Transcranial Direct Current Stimulation on Response Inhibition in Obsessive Compulsive Disorder” by Justine E.K. Centeno, Sc.M., Brown University, May 2018 Background: …
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease of motor neurons that affects at least 30,000 people in the United States at any one time …