RNA-binding proteins (RBPs) interact with a network of other proteins to form ribonucleoprotein (RNP) complexes, which are critical players throughout the lifecycle of RNA. Dysfunction …
Macrophage migration inhibitory factor (MIF) and its homolog MIF-2 are cytokine-like proteins with critical roles in immunomodulation that are upregulated in various inflammatory diseases. These …
Subcellular organization is important for maintaining cellular homeostasis within eukaryotic cells. In addition to membrane-bound organelles, membraneless compartmentalization of the cell occurs via liquid-liquid phase …
Subcellular organization is important for maintaining cellular homeostasis within eukaryotic cells. In addition to membrane-bound organelles, membraneless compartmentalization of the cell occurs via liquid-liquid phase …
Cellular homeostasis depends on proper spatiotemporal partitioning of biochemistry. In addition to the classical paradigm of subcellular division through membrane-bound organelles, cells utilize the phenomenon …
The protein ser/thr phosphatases (PSPs) dephosphorylate over 2000 of key biological targets, making them attractive therapeutic targets. The serine/threonine protein phosphatases 1 and 2B (PP1; …