Sigma receptors are a pharmacologically defined class of intracellular orphan receptors that bind a variety of psychotropic agents. The endogenous function of the sigma-2 receptor …
Abstract of CHARACTERIZING SEEDING DENSITY AS A MECHANISM OF CHEMOTHERAPY RESISTANCE IN CANCER CELLS, by Ujwal Punyamurtula, ScM, Brown University, May, 2022. While the 50% …
Human glioblastomas develop within the brain parenchyma in which there is continuous interaction of glioma cells with axon fibers, glial cells and endothelial cells. This …
Ovarian cancer is the most lethal gynecological cancer largely due to its late detection after metastasis has occurred. Stromal cells (SCs) promote cancer cell growth …
Abstract of Sigma-2 Receptor-Mediated Changes in Metabolism and Calcium Signaling, Degree ScM, Brown University, May 2019 Sigma receptors are a pharmacologically distinct family of membrane-bound …