Diffuse midline glioma (DMG) is the most aggressive primary brain tumor in children, with <10% surviving more than 2 years post-diagnosis. This tumor is inoperable …
Abstract of (Cell death associated with ENDS vapor exposure), by (Valeriia Syrovatska), ScM, Brown University, January 2023 The use of electronic nicotine delivery systems (ENDS) …
Antimicrobial resistance is a major problem and according to Centers for Disease Control and Prevention (CDC) it causes about 2.8 million antimicrobial-resistant infections every year …
Hepatitis B virus (HBV) is one of the hepadnaviridae family members that causes acute and chronic hepatitis. So far, there is no effective treatment for …
Ovarian cancer is the second most common gynecological cancer, and it is one of the most lethal types of malignancy. The 5-year relative survival rate …
Adult Hippocampal Neurogenesis (AHN) is the process through which newborn neurons are born and integrated into brain circuitry. Patients with conditions like Alzheimer’s Disease (AD) …
Substance use disorders (SUD), particularly alcohol use disorder (AUD) and opioid use disorder (OUD), represent a critical global health issue impacting millions of individuals. While …
Accurately predicting humans in vivo response to toxicant exposures is still a feat that investigators are working to improve. The current state of toxicity testing …
Plasmodium falciparum is one of the leading causes of morbidity and mortality in developing countries, infecting over 300,000 children each year and killing hundreds of …
Malaria is humans' most important parasitic disease and often the most common cause of fever in the tropics and subtropics. Because of the low efficiency …
In this thesis, the potential success of a novel drug delivery system (PDAL DDS) in the current antifungal DDS market was evaluated. Focus was placed …
Abstract of Neural Biomarker Based Parameter Optimization Using Deep Brain Stimulation for Parkinson’s Disease, by Pranav Akella, ScM., Brown University, May 2022. Introduction: Parkinson’s Disease …
Accurately predicting humans in vivo response to toxicant exposures is still a feat that investigators are working to improve. The current state of toxicity testing …
Various mixtures of melanins are responsible for determining our skin, eyes, and hair color for protection from UVR. Research has shown impaired melanin synthesis, storage …
This work analyzes the impact of polymeric morphology on the long-term sustained release of a small molecule drug, Dexamethasone, from Polycaprolactone (PCL). Changing the diffusion …
Major depressive disorder (MDD) currently affects more than 21 million people globally making it one of the most prevalent neurological conditions worldwide. Current pharmacological treatment …
Abstract of β-Lactamase Responsive Delivery of Bacteriophages for the Treatment of Multidrug Resistant Pseudomonas aeruginosa, by Alison M Veintimilla, ScM, Brown University, May, 2022. Antibiotic …