ABSTRACT Amyotrophic Lateral Sclerosis (ALS), the most common adult-onset motor neuron disease in the world, can be caused by mutations scattered along the full length …
This thesis is divided into two parts. The first part of this thesis, including chapters 1-3, examines the role of the protein Muscle specific kinase …
Amyotrophic Lateral Sclerosis (ALS) is a fatal multisystem neurodegenerative disease characterized by progressive loss of neuronal function. The disease has no cure and is fatal …
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with symptom-onset occurring in adulthood. ALS is characterized by progressive degeneration of upper and lower motor …
Abstract of The role of plastin in motor neuron disease and identifying genetic modifiers of spinal muscular atrophy, by Melissa B. Walsh, Ph. D., Brown …
Over time, more neurodegenerative disorder-linked mutations are being discovered, with more components of RNA/RNP granules containing disordered regions/domains and exhibiting the ability to undergo liquid-liquid …