Sensory input gives our brains the information they need to understand and interpret the world. Information from our eyes, ears, skin and other sensory organs …
The CACNA1C gene has the potential to generate many CaV1.2 voltage-gated calcium channel protein isoforms. CaV1.2 proteins are widely expressed throughout the body and have …
Background: Neuropathic pain is highly prevalent and expensive to treat. It is also contributing to the current opioid epidemic and deadliest overdose crisis in the …
Traumatic spinal cord injury (SCI) is a devastating disease that afflicts hundreds of thousands of people each year. Recently, spinal cord epidural electrical stimulation (EES) …
Work in the last ten years has demonstrated the existence of a third class of light-sensing neurons in the mammalian retina, intrinsically-photosensitive retinal ganglion cells …
Our ability to detect and perceive pain is driven by complex interactions that occur across the central and peripheral nervous systems. By understanding how neural …
Nicotinic acetylcholine receptors (nAChRs) mediate excitatory neurotransmission at synapses throughout the body in the neuromuscular junction and the central nervous system. The two basic types …
This study combines microelectrode array recording with optical motion capture technology in order to relate the activity of neuronal ensembles in primary motor cortex (MI) …
Ramping neural activity in prefrontal cortex is suspected to be highly involved in working memory and the temporal control of action. Here, we sought to …
Opiate abuse is a major health concern and economic burden on society with overdose deaths rising dramatically in the past decade. Synaptic plasticity within the …
The function of the retrosplenial cortex (RSC) in human cognition is a topic of rising interest in cognitive and behavioral neuroscience. So far, however, there …