Head and neck squamous cell carcinomas form a heterogeneous group of cancers of the upper aerodigestive tract, arising from the surface epithelium of the oral …
Although breast cancer screening assays exist, many are inaccessible, uninformative, and have high turnaround times, leaving a significant need for better alternatives. Here, we propose …
Head and neck squamous cell carcinoma (HNSCC) afflicts over half a million new patients each year. The major risk factors for developing this disease include …
Different types of human cells, defined by function and morphology, are typically detected and enumerated in complex mixtures using a variety of physical, optical and …
Polycomb Group (PcG) epigenetic regulators are important but not well-understood components of cellular senescence. EZH2, a PcG histone H3 lysine-27 methyltransferase, is repressed in senescent …
Exposure of the developing fetus to harmful chemicals, such as xenoestrogens, heavy metals, alcohol, and cigarette smoke, is associated with poor fetal and developmental outcomes. …
Poor-quality in utero environments are associated with adverse pregnancy outcomes and susceptibility to early and later life disease. The overarching hypothesis of this work is …
Gliomas are a family of extremely aggressive brain cancers, which, despite current treatment options, have poor prognoses. There are distinct subtypes of gliomas, and accurately …
Cardiovascular disease (CVD) is complex and chronic in nature, resulting over time from multiple factors. First, CVD rarely develops due to the presence of a …
Prions are unique proteins that can exist in multiple states. In the prion form these proteins self-replicate, directing other like molecules to adopt the prion …
