Brown University Theses and Dissertations

Brown University Library archives dissertations in accordance with the Brown Graduate School policy.

For dissertations published prior to 2008, please consult the following Dissertation LibGuide

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Description:: Checkpoint blockade therapy, which targets conserved negative regulators of immune cell activation that act as “checkpoint molecules” that govern the balance between inhibition and hyperactivation …
Year:: 2021
Contributor:: Tata, Angela Lynn (creator); Brossay, Laurent (Advisor); Vaishnava, Shipra (Reader); Bowen, Wayne (Reader); Fast, Loren (Reader); Wands, Jack (Reader); Campbell, Kerry (Reader); Brown University. Department of Molecular Biology, Cell Biology and Biochemistry (sponsor)
Genre:: theses
Subject:: Immunology; Killer cells; Cancer; Cytomegalovirus infections; Immunotherapy; Cancer--Immunotherapy; Innate immunology; Killer cell lectin-like receptor G1 (KLRG1); Programmed cell death protein-1 (PD-1)
Collection:: Biology and Medicine; Molecular Biology, Cell Biology, and Biochemistry; Theses and Dissertations

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Description:: Chitinase 3-like-1 (CHI3L1), a pleiotropic secretory molecule, plays essential roles in the pathogenesis of a variety of malignancies by boosting tumor cell proliferation, migration, epithelial-to-mesenchymal …
Year:: 2021
Contributor:: Akosman, Bedia (creator); Sanders, Jennifer (Reader); Lu, Qing (Reader); Tapinos, Nikos (Reader); Lee, Chun Geun (Advisor); Kang, Min-Jong (Reader); Elias, Jack A. (Advisor); Brown University. Biology and Medicine: Pathobiology (sponsor)
Genre:: theses
Subject:: Immunology; Cancer; Lung Cancer; Glioblastoma; Cancer--Immunotherapy; immunecheckpoints; PD-1/PD-L1; Cancer Stem Cells
Collection:: Biology and Medicine; Pathobiology; Theses and Dissertations

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