Natural killer (NK) cells are innate lymphocytes essential for host defense against viral infections and cancer. They recognize and eliminate cells termed ‘altered self’ based …
Checkpoint blockade therapy, which targets conserved negative regulators of immune cell activation that act as “checkpoint molecules” that govern the balance between inhibition and hyperactivation …
The innate and adaptive immune systems are often considered independent. The innate arm is generalized as broad and non-specific, while the adaptive arm more slowly …