The goal of this thesis was to use non-invasive quantifiable MR parameters of volume, signal intensity and T2* relaxation time to predict the biomechanical or …
Anterior cruciate ligament (ACL) disruption is a common injury, particularly in the young and active patient. ACL reconstruction surgery is the current standard of care, …
The etiology of schizophrenia (SCZ) remains elusive, though dopaminergic and genetic influences have been established as contributing factors to the disease’s pathophysiology. Current treatments for …
Cellular heterogeneity is a confounding issue for many cellular populations, and this is especially true for the study and use of adipose-derived stem/progenitor cells, or …
Theranostics is the ability to diagnose with greater detail to disease properties and tailor specialized therapeutic regiments to a patient's unique case. Advancements in nanoparticle …
Approximately half of magnetic resonance imaging (MRI) procedures require intravenously administered contrast agents image enhancement and greater diagnostic precision. The current clinical standard for MRI …
Labeling live cells for gene and protein expression is critical to a myriad of research and clinical functions. These include diagnostic imaging, enrichment of heterogeneous …
Menisci are essential for long-term knee joint function. Injuries to the menisci are common. Meniscal tears are often treated with arthroscopic partial meniscectomy (PM), a …
The elaboration of the myelin sheath around neuronal axons is a cornerstone of human brain development. This process helps establish the rapid and efficient communication …
Alcohol Use Disorder (AUD) is a chronic relapsing disease that has a major public health impact. The neurobiology of AUD remains poorly understood, and pharmacotherapies …
Across studies that use household-based survey samples, clinical diagnostic interviews, and medical records, estimates of the life-time prevalence of schizophrenia and related psychotic disorders in …