Understanding the neural dynamics of action selection, planning, and execution is necessary to treat motor system disorders. This task is complicated by the fact that …
Internal plans for movements comprise a major element of arm behavior and movement control. In the work presented in this thesis, we have identified kinematic …
In this thesis, we explored mechanisms for how the brain transforms incoming sensory information into meaningful motor output. The motor cortex is known as the …
Abstract of "Development of a Minimally Biased Approach to Neural State Space Construction and State Identification" by Alexander J. Catoya, ScM., Brown University, May 2019. …
In patients with Parkinson’s Disease (PD), Deep brain stimulation (DBS) electrode recordings have shown exaggerated, local field potentials (LFP) or bursts in the Subthalamic Nucleus …
Primates are capable of vast numbers of reach and grasp actions for a near infinite combination of perceived features. This essential primate behavior arises from …
Future brain-computer interfaces will require technologies that enable efficient, reliable and high-speed transmission of broadband multichannel neural data out of the brain with minimal number …
Deep brain stimulation (DBS) is an effective treatment for the mid/late stage Parkinson’s disease (PD), which significantly reduces the dopamine medication and improves motor symptoms. …
This study performs a systematic comparison of the information content in single unit activity (SUA) and low-and high-frequency local field potentials (lf-LFP <2Hz, and hf-LFPs >40Hz, respectively) in …</2hz,>
The primate precentral cortex receives somatosensory inputs, but very little is known about the influence of these inputs on motor cortical activity patterns in humans. …
Early life adversity (ELA) increases risk for negative health outcomes, with sex disparities in prevalence and form of ELA experienced and risk for neuropsychiatric pathology. …
Implantable brain-computer interface (BCI) systems may one day offer persons with locked-in syndrome a means of interacting and communicating with the outside world. These systems …
