High-density polyethylene (HDPE) is a widely used thermoplastic polymer with application as the material for pipeline transport systems. Due to the longterm, low-stress conditions of …
Carbohydrate-carbohydrate interactions (CCIs) between cell surface carbohydrates play an important role in cell adhesion and cell surface signaling. Glycopolymers, synthetic polymers functionalized with carbohydrate pendant …
Abstract of "Biological Application of Magnetic Nanoparticles in Targeted Therapeutics and Diagnostics" by Aruna Sigdel, Ph.D., Brown University, May 2014 Theranostics, the combination of diagnosis …
Abstract of Characterization of Temperature-Pressure Induced Morphology in High Molecular Weight Poly (Ethylene Oxide) by Sheila Velagapudi, ScM., Brown University, May 2020 The focus of …
Desirable cytocompatibility properties of nano-sized ceramics were combined with the tunable degradability and deformability of a select polymer (poly-lactide-co-glycolide, or PLGA) to optimize biological and …
Polymeric nanoparticles loaded with insulin is a highly sought-after drug delivery system in the treatment of diabetes mellitus. The goal of this experiment is to …
The overarching goal of this project is to utilize modulated differential scanning calorimetry and hot-stage x-ray diffraction to characterize and quantify the formation of oriented …
When exposed to pressures below and above their glass transition temperature (Tg) and melting temperatures (Tm) over time, both the amorphous and crystalline regions of …
This paper investigates the impact of processing conditions, specifically temperature and pressure, on inducing mesophase morphologies in Isotactic Polypropylene (iPP). iPP is a highly valued …
This work aimed to identify the morphological effects of heat and pressure on high molecular weight (300,000 kDa) polyethylene oxide, with a specific focus on …
This dissertation covers fundamental studies and application motivated research exploring the coupling between LC and polymers in unique systems. The interaction of these materials link …
This dissertation is composed around the subject of multiscale modeling of soft matter and biophysical systems with applications using large-scale computations. Specifically, it is expanded …
This work presents multiscale modeling of blood flow and polymer suspensions which requires the use of heterogeneous modeling approaches. A hybrid method based on coupling …
Poly (lactic-co-glycolic acid) (PLGA) has been widely used as a biomaterial in regenerative medicine due to its good biocompatibility and biodegradability properties. Moreover, nanotopographies have …
The ability to encapsulate drugs in a polymer delivery vehicle can have significant practical benefits. Polymers may allow for greater apparent solubility, as well as …
The ability to encapsulate drugs in a polymer delivery vehicle can have significant practical benefits. Polymers may allow for greater apparent solubility, as well as …
The main goal of this project is to examine the morphological characteristics on PMMA/PCL film casts and double walled microspheres formed in different ratios and …
This dissertation utilizes holographic exposure techniques to manipulate the periodic orientation of liquid crystal materials. Two different exposure techniques are investigated: a polarization holography interference …
Polymer folding and unfolding are fundamental processes in biology and materials science, presenting a long-standing challenge in understanding their underlying dynamics. Traditional methods for studying …
