Ischemic heart disease (IHD) is the single leading cause of death in the world and restorative treatment for IHD poses a global healthcare challenge. Myocardial …
Central nervous system disease pathologies are poorly understood in part due to the inability of animal and in vitro models to recapitulate their complexity. It …
While 2D in vitro cell culture models have been used over the decades, 3D cell culture technique is becoming increasingly important as it better replicates …
Meniscus tears are among the most frequent orthopaedic injuries that commonly affect active and young populations. These tears ultimately increase the risk of developing post-traumatic …
Cardiac patch therapies have become a promising treatment to lower the risk of heart failure after myocardial infarct to restore heart function. Engineered tissue scaffolds …
Introduction: Osteoarthritis is a debilitating joint disease that affects over 27 million Americans. Tissue engineered cartilage could be a viable option for patients that have …
The need for tissues and organs presents a complex problem for our society that can be potentially resolved through bioengineering. Thus, there is an extensive …
Sorting methods are important tools that enable cellular subpopulation isolation for basic science investigations and clinical therapies. Each method can be characterized by a set …
The systemic shift in healthcare towards precision medicine has prompted the alignment of anticancer drug selection with a more individualized approach. Moreover, advancements in 3D …
Cardiovascular engineering using human pluripotent stem cell (hPSC)-derived cardiomyocytes holds incredible potential for disease modeling, therapeutic development and testing, and cardiac regeneration. The heterogeneity and …
Due to the global burden of cardiovascular disease, there exists a need for readily available blood vessel replacements that can integrate into the patient’s native …
The advancement of three dimensional biological techniques, such as microtissues, allows for the more accurate representation of in vivo structures. Yet, the added dimension pushes …
Microtissue self-assembly and fusion are biological processes that are important to the fields of tissue engineering and biofabrication and particularly relevant to techniques such as …
Abstract Restoring Fecal Continence: An Investigation into Integrating a Synthetic Biomaterial into Colonic Mucosa By Kevin Wood BS, Dickinson College, Carlisle PA, 2011 Thesis Abstract …
Standard toxicity testing of chemicals to assess risk in humans is commonly done on animals. The problem, however, is that animals have been found to …
While many strides have been made in the field of tissue engineering since its inception, the need for a physiologically relevant biological substitute remains unmet. …
