This recorded lecture introduces students to the quantification of "brightness," ways to quantify and compare bioluminescent and fluorescent proteins, and the factors that influence Förster …
In vivo fluorescence miniature microscopy has recently proven a major advance, enabling cellular imaging in freely behaving animals. However, fluorescence imaging suffers from autofluorescence, phototoxicity, …
This recorded lecture introduces undergraduate students to the chemistry of bioluminescence and fluorescence. The lecture explains how new fluorescent proteins are discovered, whether in nature …
This recorded interview is the sixth in our Interviews with Experts series and features Elena Goun, PhD, Associate Professor of Chemistry at the University of …
Over recent years miniature microscopes have become a key tool for in vivo free behavioral studies. This technology offers the ability to measure network dynamics …
Using neuroscientists' tools of the trade one can image in independent animals either the brain or the spinal cord. Yet understanding many biological processes such …
State-of-the-art imaging tools rely on a restrained preparation, limiting natural behavior while measuring cellular activity via fluorescence (FL). Recently, advances in wearable microscopy expanded the …
Bioluminescent molecules for imaging and modifying neural activity are increasingly becoming viable tools for in vivo use and have the potential to overcome many of …
As an alternative to fluorescent imaging, we are developing calcium-dependent, genetically-encoded molecules using bioluminescent probes. Bioluminescence is chemically generated light that occurs when a photon-containing …
