Myeloid-derived suppressor cells (MDSCs) are an immunosuppressive, heterogeneous population of cells upregulated in cancer and other pathologic conditions. DNA methylation (DNAm) is well known to …
People living with HIV are 3 to 10 times more likely to develop Hodgkin’s lymphoma (HL) than the HIV-uninfected population. This risk swells to 20-30x …
Neutrophils are myeloid derived leukocytes that play an essential role in the innate immune system. They are often referred to as “first responders” to sites …
Our project aimed to study the effects of temozolomide on T-cell killing of glioblastoma and colorectal cancer cells. To do so, we first examined sensitivity …
Radiation-associated sarcoma (RAS) describes the 10% of soft-tissue sarcoma cases linked to a previous ionizing radiation exposure event that exhibit worse survival outcomes than their …
Gastric cancer remains a major worldwide health problem and is considered the second most common cause of cancer death in the world. Oncogenic stress response …
Gastric cancer remains a major worldwide health problem and is considered the second most common cause of cancer death in the world. Oncogenic stress response …
Background: Drug resistance is a significant contributor to cancer treatment failure and patient mortality. Combination therapies can prevent the selective evolutionary pressure that allows resistant …
Pancreatic and colorectal cancers remain two of the leading causes of cancer deaths in the United States, ranking third (8%) and second (9%) respectively as …
Colorectal cancer (CRC) is the 3rd deadliest cancer in Rhode Island. In 2018, 75.7% of eligible Rhode Islanders met the United States Preventive Services Task …
Following cancer treatment, patients can experience ongoing physical and psycho-social stress. These same cancer diagnoses and treatment experiences may also impact the well-being of caregivers …
