Myeloid-derived suppressor cells (MDSCs) are an immunosuppressive, heterogeneous population of cells upregulated in cancer and other pathologic conditions. DNA methylation (DNAm) is well known to …
The interplay of neurons and cancer has been identified as a driver of cancer progression. Small Cell Lung Cancer (SCLC) is a high-grade, neuroendocrine tumor …
Primary Central Nervous System Lymphoma (PCNSL) is a rare and aggressive extranodal form of non-Hodgkin lymphoma (NHL) that accounts for approximately 5% of all primary …
Introduction: Any cancer treatment can greatly damage ovarian reserve and threaten future fertility. Various reproductive strategies exist to aid in family-building. An important distinction must …
Introduction: Dexamethasone is widely utilized in neuro-oncology, primarily for managing cerebral edema associated with brain tumors. While it effectively reduces inflammation and intracranial pressure, its …
People living with HIV are 3 to 10 times more likely to develop Hodgkin’s lymphoma (HL) than the HIV-uninfected population. This risk swells to 20-30x …
Neutrophils are myeloid derived leukocytes that play an essential role in the innate immune system. They are often referred to as “first responders” to sites …
Introduction Chordoma, a rare yet highly morbid cancer arising from notochordal progenitor cells along the spinal axis, relies on invasive en bloc surgical resection and …
This qualitative study examines the influence of spirituality in the lives of cancer patients undergoing treatment. Through semi-structured interviews with 20 adult cancer patients, the …
Glioblastoma accounts for over half of primary malignant brain tumors in adults. Five-year survival is <10%. Age, neurologic performance, extent of resection, and certain molecular …
Our project aimed to study the effects of temozolomide on T-cell killing of glioblastoma and colorectal cancer cells. To do so, we first examined sensitivity …
Myeloproliferative neoplasms (MPNs) are a class of blood cancers derived from the clonal expansion of aberrant hematopoietic stem/progenitor cells in the bone marrow. The three …
Radiation-associated sarcoma (RAS) describes the 10% of soft-tissue sarcoma cases linked to a previous ionizing radiation exposure event that exhibit worse survival outcomes than their …
Gastric cancer remains a major worldwide health problem and is considered the second most common cause of cancer death in the world. Oncogenic stress response …
Gastric cancer remains a major worldwide health problem and is considered the second most common cause of cancer death in the world. Oncogenic stress response …
My project focuses on reducing the toxicity that the chemotherapy treatment, paclitaxel, leaves on peripheral neurons by applying low-intensity ultrasound to minimize side effects such …
My project focuses on reducing the toxicity that the chemotherapy treatment, paclitaxel, leaves on peripheral neurons by applying low-intensity ultrasound to minimize side effects such …
