Optical design of a bench-top retinal prosthesis systemtextChoconta, PaulacreatorToussaint, KimaniReaderLee, JonghwanAdvisorMigliori, MichaelReaderBrown University. Biology and Medicine: Biomedical Engineeringsponsor2020iii, 33 p.born digitalThesis (Sc. M.)--Brown University, 2020thesesRetinal prostheses stimulate nerve cells at different target locations along the visual pathway treat vision loss. Electrode-based retinal prosthesis implants have been used to restore vision in subjects with vision loss. These implants have shown favorable results, but there are limitations, such as limited resolution and reduced functionality over time. To bypass the limitations of electrode-based implants, a contact-free and spatially selective stimulation method such as optical stimulation of nerve cells can be used. Near-infrared light can be used to activate neuron cells by inducing a temperature change in target cells without tissue damage. This paper focuses on the NIR stimulation of retinal ganglion cells to optimize optical parameters for a bench-top retinal prosthesis system and examines the feasibility of non-invasive retinal prosthesis through the numerical simulation of laser projection on the retina.retinal prostheticsnear infrared neuronal stimulationEnglishRPB2020072010.26300/ax6s-w788In CopyrightCollection is open for research.