- Title Information
- Title
- Association between coffee intake and coronary heart disease among postmenopausal women
- Type of Resource
- text
- Name:
Personal
- Name Part
- Kim, Yery
- Role
- Role Term:
Text
- creator
- Name:
Personal
- Name Part
- Eaton, Charles
- Role
- Role Term:
Text
- Advisor
- Name:
Personal
- Name Part
- Kelsey, Karl
- Role
- Role Term:
Text
- Reader
- Name:
Corporate
- Name Part
- Brown University. Department of Epidemiology
- Role
- Role Term:
Text
- sponsor
- Origin Information
- Copyright Date
- 2020
- Physical Description
- Extent
- , None p.
- digitalOrigin
- born digital
- Note:
thesis
- Thesis (Sc. M.)--Brown University, 2020
- Genre (aat)
- theses
- Abstract
- Background: Association between long-term habitual coffee intake and risk of coronary heart disease (CHD) among postmenopausal women is unclear.
Objective: The objective was to examine the dose-response relationship between total, caffeinated, and decaffeinated coffee intake and risk of CHD in a large cohort of postmenopausal women enrolled in the Women’s Health Initiative (WHI).
Design: A substudy (Observational Study) in 86,459 postmenopausal women within the Women's Health Initiative (WHI) with measured coffee intake were followed for an average of 11.5y for CHD events. The multivariable-adjusted models were computed by using Cox proportional hazards regression to evaluate the association between coffee intake and CHD.
Results: Of the 86,459 postmenopausal women, 5,899 CHD events occurred. Drinking ≥2 cups caffeinated coffee was significantly associated with reduced risk of CHD in a dose response manner. After fully adjusting for potential covariates, drinking 2-3 cups of caffeinated coffee was associated with a 8% reduction in the risk of CHD (HR: 0.92; 95% CI: 0.86, 0.98) while ≥ 4 cups/d of caffeinated coffee intake was associated with 13% of reduction in CHD risk (HR: 0.87; 95%CI: 0.78, 0.96), p trend =0.001. Decaffeinated coffee intake showed no clear association with CHD; however, there was no increased CHD risk with higher consumption.
Conclusion: Long-term caffeinated coffee intake (≥2 cups) may be beneficial on reducing CHD risk among postmenopausal women.
- Subject (fast)
(authorityURI="http://id.worldcat.org/fast", valueURI="http://id.worldcat.org/fast/00914091")
- Topic
- Epidemiology
- Subject (fast)
(authorityURI="http://id.worldcat.org/fast", valueURI="http://id.worldcat.org/fast/01082238")
- Topic
- Public health
- Subject (fast)
(authorityURI="http://id.worldcat.org/fast", valueURI="http://id.worldcat.org/fast/00879535")
- Topic
- Coronary heart disease
- Subject (fast)
(authorityURI="http://id.worldcat.org/fast", valueURI="http://id.worldcat.org/fast/00866301")
- Topic
- Coffee
- Language
- Language Term (ISO639-2B)
- English
- Record Information
- Record Content Source (marcorg)
- RPB
- Record Creation Date
(encoding="iso8601")
- 20200720
- Access Condition:
rights statement
(href="http://rightsstatements.org/vocab/InC/1.0/")
- In Copyright
- Access Condition:
restriction on access
- Collection is open for research.