<mods:mods xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" ID="Seidman" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/mods/v3/mods-3-6.xsd">
    <mods:titleInfo>
        <mods:title>Identical by descent tracts in unphased genotypes</mods:title>
    </mods:titleInfo>
    <mods:name type="personal">
        <mods:namePart>Seidman, Daniel</mods:namePart>
        <mods:role>
            <mods:roleTerm type="text">creator</mods:roleTerm>
        </mods:role>
    </mods:name>
    <mods:name type="personal">
        <mods:namePart>Istrail, Sorin</mods:namePart>
        <mods:role>
            <mods:roleTerm type="text">advisor</mods:roleTerm>
        </mods:role>
        <mods:affiliation>Brown University. Department of Computer Science</mods:affiliation>
    </mods:name>

    <mods:name type="corporate">
        <mods:namePart>Brown University. Undergraduate Teaching and Research Award</mods:namePart>
        <mods:role>
            <mods:roleTerm type="text">research program</mods:roleTerm>
        </mods:role>

    </mods:name>

    <mods:typeOfResource>still image</mods:typeOfResource>
    <mods:genre authority="aat">posters</mods:genre>
    <mods:originInfo>
        <mods:place>
            <mods:placeTerm type="text">Providence</mods:placeTerm>
        </mods:place>
        <mods:publisher>Brown University</mods:publisher>
        <mods:dateCreated encoding="w3cdtf">2015-08-07</mods:dateCreated>
    </mods:originInfo>
    <mods:physicalDescription>
        <mods:extent>1 poster</mods:extent>
        <mods:digitalOrigin>reformatted digital</mods:digitalOrigin>
    </mods:physicalDescription>
    <mods:abstract>I am designing a program to be able to identify Identical by Descent (IBD) tracts
        in unphased genotypes. In many cases, when genomes are sequenced, it can be difficult to
        localize which fragments of known sequence belong on which of a set of complimentary
        chromosomes, and as such, sequence data can be ambiguous. Usually this ambiguity is resolved
        through phasing, where the each piece of known sequence is localized to one particular
        complimentary chromosome via statistical estimates and knowledge of relationships between
        sequences. Once done, it is possible to determine if two portions of DNA sequence in two
        separate chromosomes share a common ancestral origin. However, the common ancestral origin
        information (a.k.a. Identical By Descent) would be very useful for the statistics involved
        in phasing, thus the ability to determine the tracts of Identical by Descent DNA sequence
        would assist the statistical accuracy of the phasing if it could be done first. That is what
        my program currently aims to accomplish, as efficiently in both time and memory
        possible.</mods:abstract>
    <mods:subject authority="lcsh">
        <mods:topic>Nucleotide sequence</mods:topic>
    </mods:subject>
    <mods:subject authority="lcsh">
        <mods:topic>Computational biology</mods:topic>
    </mods:subject>
    <mods:subject authority="local">
        <mods:topic>Identical by descent</mods:topic>
    </mods:subject>
<mods:identifier xmlns:xlink="http://www.w3.org/1999/xlink" type="doi">10.26300/zsqr-4b69</mods:identifier></mods:mods>