Assessing the efficacy of silver-doped antimicrobial coatings on prosthetic liners


Amputations are commonplace in orthopedic surgery as roughly 185,000 patients undergo an amputation each year. This number will continue to rise, as projections call for an estimated 50 percent increase to the amputee population in the next 35 years. With such a large patient pool, proper care and support for amputees is crucial. One of the leading issues facing amputee patients is late developing antibiotic-resistant bacterial infections in the stump of the patient. This is especially true with amputees who utilize prosthetic limbs. The enclosed design of the prosthetic socket often causes friction, sweat and debris build-up at the prosthetic-stump interface. Coupled with body heat, these factors result in a favorable condition for skin irritation, bacterial growth and eventual infection.\t\n\nThe objective of this study was to assess the antimicrobial properties of a silver-doped matrix coating on seven antibiotic-resistant pathogens commonly associated with infection.


Haglin, Jack, "Assessing the efficacy of silver-doped antimicrobial coatings on prosthetic liners" (2015). Summer Research Symposium. Brown Digital Repository. Brown University Library.



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    Each year, Brown University showcases the research of its undergraduates at the Summer Research Symposium. More than half of the student-researchers are UTRA recipients, while others receive funding from a variety of Brown-administered and national programs and fellowships and go …