Title Information
Title
Exploring triphenylene ethynylene structures as MALDI matrices
Name: Personal
Name Part
Mayans, David
Role
Role Term: Text
creator
Name: Personal
Name Part
Zimmt, Matt
Role
Role Term: Text
advisor
affiliation
Brown University. Department of Chemistry
Name: Corporate
Name Part
Brown University. Chemistry Research
Role
Role Term: Text
research program
Type of Resource
still image
Genre (aat) (usage="primary")
posters
Origin Information
Place
Place Term: Text
Providence
Publisher
Brown University
Date Created (keyDate="yes", encoding="w3cdtf")
2015-08-07
Physical Description
Extent (supplied="yes")
1 poster
digitalOrigin
reformatted digital
Language (usage="primary")
Language Term
eng
Abstract
MALDI continues to be a useful method of mass spectrometry for a wide range of biological molecules. This poster explores the use of several preliminary triphenylene ethynylene (TPEE) structures that may be useful as matrices in MALDI spectrometry. Three electron-donating TPEEs were synthesized and analyzed and two electron-withdrawing TPEEs were synthesized and compared to TCNQ. One of the electron-donating matrices and one of the electron-withdrawing matrices showed significant promise as effective MALDI matrices, demonstrating minimal fragmentation, low matrix peaks, and high analyte signal strength.
Subject (LCSH)
Topic
Matrix-assisted laser desorption-ionization
Subject (LCSH)
Topic
Mass spectrometry
Identifier: DOI
10.26300/gy86-3475