Title Information
Title
Extracellular field potential recordings in hippocampal CA1 and dorsal horn of wild type and TRPV1-Cre x ChR2 mice
Name: Personal
Name Part
Polynice, Shahena
Role
Role Term: Text
creator
Name: Personal
Name Part
Kauer, Julie
Role
Role Term: Text
advisor
affiliation
Brown University. Department of Neuroscience
Name: Corporate
Name Part
Brown University. Undergraduate Teaching and Research Award
Role
Role Term: Text
research program
Type of Resource
still image
Genre (aat) (usage="primary")
posters
Origin Information
Place
Place Term: Text
Providence
Publisher
Brown University
Date Created (keyDate="yes", encoding="w3cdtf")
2015-08-07
Physical Description
Extent (supplied="yes")
1 poster
digitalOrigin
reformatted digital
Language (usage="primary")
Language Term
eng
Abstract
TRPV1 is a heat- and capsaicin-activated receptor expressed on C-fibers, nociceptors that carry pain information from the periphery to the brain. Channelrhodopsin 2 (ChR2) is a blue light-activated ion channel not normally expressed in animals. In mice genetically engineered to express ChR2 in Trpv1-expressing C fiber afferents, blue light stimulation of the paw activates these pain fibers, mimicking a painful stimulus.
Subject (LCSH)
Topic
Hipppocampus (Brain)
Identifier: DOI
10.26300/8c7m-ha62