Title Information

Non Sort

The

Title

immediate effects of gonadotoxic agents on the viability of the mammalian ovary: are multidrug resistant transporters protective?

Name: Personal

Name Part

Voigt, Niesha

Role

Role Term: Text (marcrelator)

author

affiliation

Brown University. Alpert Medical School

Name: Personal

Name Part

Oulhen, Nathalie

Role

Role Term: Text (marcrelator)

author

affiliation

Brown University. Department of Molecular Biology, Cell Biology and Biochemistry

Name: Personal

Name Part

Wessel, Gary M.

Role

Role Term: Text (marcrelator)

author

affiliation

Brown University. Department of Molecular Biology, Cell Biology and Biochemistry

Name: Personal

Name Part

Brayboy, Lynae M.

Role

Role Term: Text (marcrelator)

author

affiliation

Women & Infants Hospital of Rhode Island

Type of Resource

text

Genre (aat)

abstracts (summaries)

Origin Information

Date Created (keyDate="yes", encoding="w3cdtf")

2016

Language

Language Term

eng

Note (displayLabel="Scholarly concentration")

Women's Reproductive Health

Abstract

Chemotherapy-induced ovarian toxicity is collateral damage that is becoming a leading cause of ovarian insufficiency, which prejudices the patient to premature onset of menopause-associated risks such as osteoporosis, increased cardiovascular risk, and sexual dysfunction in addition to infertility. The purpose of this research study is to determine the immediate gonadotoxic defense mechanisms imparted by multidrug resistant transporters (MDRs) in the two major cell types of the follicle, the granulosa cells and the oocytes by assessing the ovary in situ.

Subject (LCSH)

Topic

Ovaries

Topic

Effect of chemicals on

Access Condition: use and reproduction (href="https://creativecommons.org/licenses/by-nc/4.0/")

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Access Condition: logo (href="https://licensebuttons.net/l/by-nc/4.0/88x31.png")

Identifier: DOI

10.26300/sqqe-y390