Representation of drug use in biomedical standards, clinical text, and research measures Carter, Elizabeth W. author University of Vermont. Center for Clinical and Translational Science Sarkar, Indra Neil author Brown University. Center for Biomedical Informatics Melton, Genevieve B. author Chen, Elizabeth S. author Brown University. Center for Biomedical Informatics text papers (documents) 2015 p. 376-385 eng Drug misuse is a prominent cause of morbidity and mortality in the United States. Recent focus on behavioral and social domains in the electronic health record (EHR) has highlighted the need for comprehensive examination social history information, such as drug use. In this study, representation of drug use was examined in three types of sources: (1) standards from HL7 and openEHR, (2) clinical text from publicly accessible clinical notes and a local EHR, and (3) research measures from the PhenX Toolkit and CDE Browser. In total, 27 elements were identified across the examined sources, revealing a diverse set of values that were found to be associated with drug use type, frequency, method, time frame, and amount. The findings of this study provide insight into the representation of drug use information that may contribute to efforts for standardizing collection and use of these data to support clinical care and research This work is funded by National Library of Medicine/National Institutes of Health grant R01LM011364. Drug use AMIA Annual Symposium Proceedings 2015:376-85 This work is licensed under a Creative Commons CC BY 4.0 License 26958169