Title Information
Title
Mining and visualizing family history associations in the electronic health record: a case study for pediatric asthma
Name: Personal
Name Part
Chen, Elizabeth S.
Role
Role Term: Text (marcrelator)
author
Name: Personal
Name Part
Melton, Genevieve B.
Role
Role Term: Text (marcrelator)
author
Name: Personal
Name Part
Wasserman, Richard C.
Role
Role Term: Text (marcrelator)
author
Name: Personal
Name Part
Rosenau, Paul T.
Role
Role Term: Text (marcrelator)
author
Name: Personal
Name Part
Howard, Diantha B.
Role
Role Term: Text (marcrelator)
author
Name: Personal
Name Part
Sarkar, Indra Neil
Role
Role Term: Text (marcrelator)
author
Type of Resource
text
Genre (aat)
papers (documents)
Origin Information
Date Created (keyDate="yes", encoding="w3cdtf")
2015
Language
Language Term: Code (ISO639-2B)
eng
Note (displayLabel="Source")
Electronic Health Record
Note (displayLabel="Method")
Data Mining
Note (displayLabel="Condition")
Asthma
Abstract
Asthma is the most common chronic childhood disease and has seen increasing prevalence worldwide. While there is existing evidence of familial and other risk factors for pediatric asthma, there is a need for further studies to explore and understand interactions among these risk factors. The goal of this study was to develop an approach for mining, visualizing and evaluating association rules representing pairwise interactions among potential familial risk factors based on information documented as part of a patient's family history in the electronic health record. As a case study, 10,260 structured family history entries for a cohort of 1,531 pediatric asthma patients were extracted and analyzed to generate family history associations at different levels of granularity. The preliminary results highlight the potential of this approach for validating known knowledge and suggesting opportunities for further investigation that may contribute to improving prediction of asthma risk in children.
Note: funding
This research was supported in part by the National Library of Medicine of the National Institutes of Health under award number R01LM011364
Note
Paper presented at the 2015 AMIA Annual Symposium
Subject (Local)
Topic
Family history
Related Item: Host (displayLabel="Published in")
Title Information
Title
AMIA Annual Symposium Proceedings
Origin Information
Date Created
2015
Date Created (keyDate="yes", encoding="w3cdtf")
2015
Physical Description
Extent
p. 396-405
Identifier: PubMed Central ID
PMCID: PMC4765567
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