Title Information
Title
Biodissolution and cellular response to MoO3 nanoribbons and a new framework for early hazard screening for 2D materials.
Abstract
Two-dimensional materials are a class of ultra-thin but highly functional materials that promise improvements in semiconductor electronics, energy capture and storage, or catalysis, as compared to traditional materials. The fiber- or plate-like shape and nanosize thickness of these materials raises questions regarding their fate, toxicity and risk throughout production and use. Here we present a framework to evaluate the potential hazard of 2D materials, considering both biopersistence and cytotoxicity. The aim of this approach is to rapidly identify and prioritize materials with the highest potential risk for more detailed study. A novel 2D material, MoO3 was evaluated using the framework, and determined to be of low priority for further evaluation due to its rapid degradation into low-hazard dissolution products.
Name
Name Part
Evan Gray
Role
Role Term (marcrelator) (authorityURI="http://id.loc.gov/vocabulary/relators", valueURI="http://id.loc.gov/vocabulary/relators/aut")
Author
Name
Name Part
Browning, Cynthia
Role
Role Term (marcrelator) (authorityURI="http://id.loc.gov/vocabulary/relators", valueURI="http://id.loc.gov/vocabulary/relators/aut")
Author
Name
Name Part
Wang, Mengjing
Role
Role Term (marcrelator) (authorityURI="http://id.loc.gov/vocabulary/relators", valueURI="http://id.loc.gov/vocabulary/relators/aut")
Author
Name
Name Part
Gion, Kyle
Role
Role Term (marcrelator) (authorityURI="http://id.loc.gov/vocabulary/relators", valueURI="http://id.loc.gov/vocabulary/relators/aut")
Author
Name
Name Part
Chao, Eric
Role
Role Term (marcrelator) (authorityURI="http://id.loc.gov/vocabulary/relators", valueURI="http://id.loc.gov/vocabulary/relators/aut")
Author
Name
Name Part
Koski, Kristie
Role
Role Term (marcrelator) (authorityURI="http://id.loc.gov/vocabulary/relators", valueURI="http://id.loc.gov/vocabulary/relators/aut")
Author
Name
Name Part
Kane, Agnes
Role
Role Term (marcrelator) (authorityURI="http://id.loc.gov/vocabulary/relators", valueURI="http://id.loc.gov/vocabulary/relators/aut")
Author
Name
Name Part
Hurt, Robert
Role
Role Term (marcrelator) (authorityURI="http://id.loc.gov/vocabulary/relators", valueURI="http://id.loc.gov/vocabulary/relators/aut")
Author
Origin Information
Date Created
2018-11-07
Subject (Local)
Topic
2D nanomaterials
Subject (Local)
Topic
biopersistence
Subject (Local)
Topic
cytotoxicity
Subject (Local)
Topic
nanotoxicity
Type of Resource
text
Genre
peer-reviewed journal article
Note: funding
This research was supported by the National Institute of Environmental Health Sciences (NIEHS) Superfund Research Program of the National Institutes of Health under award number P42ES013660.