Depressive symptoms and engagement in HIV care following ART initiation

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Overview

Title
Depressive symptoms and engagement in HIV care following ART initiation
Contributors
Bengtson, Angela M. (Author)
Pence, Brian W. (Author)
Mimiaga, Matthew J. (Author)
Gaynes, Bradley N. (Author)
Moore, Richard (Author)
Christopoulos,Katerina (Author)
O’Cleirigh, Conall (Author)
Grelotti, David (Author)
Napravnik, Sonia (Author)
Crane, Heidi (Author)
Mugavero, Michael (Author)
Date Created
2018
Abstract
The effect of depressive symptoms on progression through the human immunodeficiency virus (HIV) treatment cascade is poorly characterized. We included participants from the Centers for AIDS Research Network of Integrated Clinic Systems cohort who were antiretroviral therapy (ART) naive, had at least 1 viral load and HIV appointment measure after ART initiation, and a depressive symptom measure within 6 months of ART initiation. Recent depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9) and categorized using a validated cut point (PHQ-9 ≥10). We followed participants from ART initiation through the first of the following events: loss to follow-up (>12 months with no HIV appointment), death, administrative censoring (2011–2014), or 5 years of follow-up. We used log binomial models with generalized estimating equations to estimate associations between recent depressive symptoms and having a detectable viral load (≥75 copies/mL) or missing an HIV visit over time.
Keywords
HIV
depression
mental health
HIV treatment cascade
viral load

Citation

Bengtson, Angela M., Pence, Brian W., Mimiaga, Matthew J., et al., "Depressive symptoms and engagement in HIV care following ART initiation" (2018). Open Access Publications and Presentations. Brown Digital Repository. Brown University Library. https://repository.library.brown.edu/studio/item/bdr:841002/

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  • This collection contains copies of presentations and open access publications (green and gold) and pre-prints and author manuscripts (post-prints) of publications authored and/or co-authored by Dr. Bengtson.

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