<mods:mods xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-4.xsd">
  <mods:titleInfo>
    <mods:title>The Role of Type 2 Polyaxonal Amacrine Cells (PAC2) in mediating light adaptation</mods:title>
  </mods:titleInfo>
  <mods:abstract>We propose that selected ipRGCs form electrical gap junctions with a special type of wide-eld amacrine cell known as the Type 2 Polyaxonal Amacrine Cell (PAC2). These PACs, in turn, distribute the intensity information across the retina and modulate the contrast-encoding pathway. We tested this hypothesis by reconstructing a PAC2 and its postsynaptic partners in a serial electron microscopy dataset. The axons of PAC2s were scanned for membrane swelling or the presence of vesicles in order to reconstruct the BCs, RGCs and ACs receiving input from the PAC2s.</mods:abstract>
  <mods:name>
    <mods:namePart>Beltoja, Marjo</mods:namePart>
    <mods:role>
      <mods:roleTerm authority="marcrelator" authorityURI="http://id.loc.gov/vocabulary/relators" valueURI="http://id.loc.gov/vocabulary/relators/cre">Creator</mods:roleTerm>
    </mods:role>
  </mods:name>
 <mods:name type="personal">
<mods:namePart>Berson, David</mods:namePart>
<mods:role>
<mods:roleTerm type="text" authority="marcrelator">advisor</mods:roleTerm>
</mods:role>
</mods:name>
<mods:name type="personal">
<mods:namePart>Hai, Chi-Ming</mods:namePart>
<mods:role>
<mods:roleTerm type="text" authority="marcrelator">reader</mods:roleTerm>
</mods:role>
</mods:name>
<mods:name type="corporate">
<mods:namePart>Brown University</mods:namePart>
<mods:namePart>Division of Biology and Medicine</mods:namePart>
<mods:role>
<mods:roleTerm type="text" authority="marcrelator">sponsor</mods:roleTerm>
</mods:role>
</mods:name>
<mods:originInfo>
<mods:copyrightDate>2018</mods:copyrightDate>
</mods:originInfo>
<mods:physicalDescription>
<mods:extent>61 p.</mods:extent>
<mods:digitalOrigin>born digital</mods:digitalOrigin>
</mods:physicalDescription>
<mods:language>
<mods:languageTerm type="code" authority="iso639-2b">eng</mods:languageTerm>
</mods:language>
<mods:note type="thesis">Senior thesis (AB)--Brown University, 2018</mods:note>
<mods:note displayLabel="Concentration">Biophysics</mods:note>
<mods:subject authority="fast" authorityURI="http://id.worldcat.org/fast" valueURI="http://id.worldcat.org/fast/1096191">
<mods:topic>Retina</mods:topic>
</mods:subject>
  <mods:subject authority="local">
    <mods:topic>ipRGCs</mods:topic>
  </mods:subject>
  <mods:subject authority="local">
    <mods:topic>contrast</mods:topic>
  </mods:subject>
  <mods:subject authority="local">
    <mods:topic>amacrine</mods:topic>
  </mods:subject>
  <mods:subject authority="local">
    <mods:topic>intensity</mods:topic>
  </mods:subject>
  <mods:typeOfResource>text</mods:typeOfResource>
  <mods:genre authority="aat">theses</mods:genre>
  <mods:identifier type="doi">10.26300/xarg-hw87</mods:identifier><mods:accessCondition type="rights statement" xlink:href="http://rightsstatements.org/vocab/InC/1.0/">In Copyright</mods:accessCondition><mods:accessCondition type="restriction on access">Collection is open for research.</mods:accessCondition></mods:mods>