Correlates of death during an outpatient treatment episode for opioid use disorder: A national study

Goldman, Jacqueline E.

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Overview

Year:: 2019
Contributor:: Goldman, Jacqueline E (creator); Marshall, Brandon (Advisor); Samuels, Elizabeth (Reader); Brown University. Department of Epidemiology (sponsor)
Genre:: theses
Subject:: Drugs--Overdose; Opiod use disorder; Medications for addiction
Extent:: 7, 27 p.
DOI: https://doi.org/10.26300/w0em-fn62

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Abstract:: Background: As the burden of opioid use disorder increases in the United States, manifold federal and state initiatives have sought to increase access to treatment for opioid use disorder (OUD), which can encompass both behavioral and pharmaceutical treatment modalities. Although the evidence base for outpatient treatment for OUD—including medications for opioid use disorder—is substantial, few studies have examined the risk factors for fatality experienced during a treatment episode. Methods: In order to evaluate correlates of death during an outpatient treatment for OUD treatment, data from the 2016 Treatment Episode Data Set-Discharges (TEDS-D) were used. To determine the correlates of mortality during an outpatient treatment episode for OUD, we constructed a pooled logistic regression model, stratified by use of medication for addiction treatment (MAT), to control for the length of treatment episodes and to identify the independent characteristics that may lead to differences in the odds of mortality experienced during treatment. Findings: There were total of 41,781 outpatient treatment episodes for OUD that were included in our analysis, 1,656 (4%) resulted in fatality. Many factors correlated with death during treatment were similar for individuals who did and did not receive MAT. However, non-White race was only significantly associated with fatality in treatment episodes involving MAT. On the other hand, male sex and reporting intravenous drug use at admission were associated with fatality only for treatment episodes that did not involve MAT Conclusions: In this national study of outpatient treatment episodes for OUD, we found differences in age, sex, region, drug use history, treatment setting, treatment history significantly affected the risk of death during treatment. As more people become engaged with treatment, facilities need to assess how they can deliver optimal treatment for all patients regardless of personal characteristics.
Notes:: Thesis (Sc. M.)--Brown University, 2019

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Rights: In Copyright
Restrictions on Use: Collection is open for research.

Citation

Goldman, Jacqueline E., "Correlates of death during an outpatient treatment episode for opioid use disorder: A national study" (2019). Epidemiology Theses and Dissertations. Brown Digital Repository. Brown University Library. https://doi.org/10.26300/w0em-fn62

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Epidemiology Theses and Dissertations

Theses and Dissertations for the Epidemiology department.
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