Objective – To determine an age-specific anti-mullerian hormone (AMH) reference range for Samoan women and to examine the associations of AMH with adiposity, dietary, and reproductive factors. Design – Cross-sectional study. Setting – Community-based sample. Participants – 681 Samoan women with no known reproductive disorders, reproductive surgeries, or contraceptive use, age 25-51. Main Outcome(s) – AMH levels. Results –AMH was negatively associated with age. AMH decline with age in Samoan women is best described by a cubic model. AMH was not associated with body mass index (BMI) and insulin resistance. It was negatively associated with percent calories from dietary protein and positively associated with total dietary sugars. Conclusions – This study was the first to construct an age-specific AMH reference range for Samoan women. Our results contribute to the literature on population-specific AMH reference ranges. This study provides further evidence of the seemingly paradoxical relationship between adiposity and fecundity in Samoan women. Further longitudinal research needs to be done to examine these associations and non-associations more thoroughly.
O'Brien, Grace,
"Age-specific anti-mullerian hormone reference range for Samoan women age 25-51"
(2019).
Epidemiology Theses and Dissertations.
Brown Digital Repository. Brown University Library.
https://doi.org/10.26300/7pya-bv62
