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Year:: 2018
Contributor:: Maxwell, Aaron W.P (Creator); Park, William K.C. (Creator); Niewchas, Abbigail (Creator); Walsh, Edward (Creator); Baird, Grayson L. (Creator); Dupuy, Damian E. (Creator); Brown University. Karen T. Romer Undergraduate Teaching and Research Awards (research program)
Subject:: Liver; Image Guided Thermal Ablation (IGTA); hepatocellular carcinoma (HCC)
DOI: https://doi.org/10.26300/ad3w-2596

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Abstract:: According to the World Health Organization, approximately 90% of the 1.45 million deaths caused by viral hepatitis can be attributed to chronic HBV and HCV infections that lead to hepatocellular carcinoma (HCC) and cirrhosis. Though surgical resection and transplantation are advocated as first line therapies, they are not viable options for the majority of patients because of the underlying severity of their liver dysfunction. One appealing alternative treatment to such patient populations is Image Guided Thermal Ablation (IGTA). Though a considerably safer option, it is known to have a relatively high rate of local tumor progression. To mitigate the inconsistent success of IGTA, Park et al., have developed a novel thermal accelerant (TA) agent capable of augmenting microwave energy from a distance usually unattainable by a single antenna in vivo. Previous research has proven the TA substance successful in increasing ablation volumes in a variety of porcine tissue, most notably in the liver.

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Use and Reproduction: This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license

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Maxwell, Aaron W.P, Park, William K.C., Niewchas, Abbigail, et al., "Thermometric Measurements of Swine Liver By MRI During Microwave Ablation: The Use of Thermal Accelerant to Facilitate Complete Ablation of Tumors" (2018). Summer Research Symposium. Brown Digital Repository. Brown University Library. https://doi.org/10.26300/ad3w-2596

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Summer Research Symposium

Each year, Brown University showcases the research of its undergraduates at the Summer Research Symposium. More than half of the student-researchers are UTRA recipients, while others receive funding from a variety of Brown-administered and national programs and fellowships and go …
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Thermometric Measurements of Swine Liver By MRI During Microwave Ablation: The Use of Thermal Accelerant to Facilitate Complete Ablation of Tumors