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Year:: 2024
Contributor:: Marina Espinosa (creator); McParland, Emily (creator); Serrano, Jayleann (creator); Roberts, Thomas (creator); Emily McParland (advisor); Leadership Alliance-Summer Research Early Identification Program (SR-EIP) (research program)
Genre:: posters
Subject:: Eye; Muscles; Vertebrates--Dissection
Extent:: 1 poster

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Description

Abstract:: All vertebrates have six extraocular (EO) muscles that insert into the outer layer of the eye that facilitate eye motion with high speed and precision. They consist of four rectus muscles – superior, inferior, medial, and lateral rectus -- that originate in the back of the eye and two uniquely oriented oblique muscles – superior and inferior oblique. Despite high conservation of EO muscle morphology, a broad interspecies comparative study of extraocular muscle anatomy has not been conducted. Because important contractile properties of muscles (e.g., maximum force and maximum strain) are also conserved across vertebrates, anatomical measures like muscle length and cross-sectional area can inform our understanding of extraocular muscle mechanical function. Here, we utilize open-sourced diffusible iodine-based contrast-enhanced computed tomography (DiceCT) scans to construct three-dimensional models of EO muscles and eyes from multiple vertebrate species. From these models and gross dissection, we measured eye diameter and volume, and EO muscle length and cross-sectional area to functionally assess similarities and differences of vertebrate species. We compared co-contracting muscle pair metrics across species with differing behaviors and morphologies such as lateral eyed and frontal eyed species. We also compared the same muscle metrics with eye size to assess scaling of the EO muscle system across different species and muscles. This study pilots a broad comparative analysis of vertebrate EO muscle function, aiming to quantify conserved and derived traits in muscular eyes.

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Use and Reproduction: All rights reserved
Rights: In Copyright
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Citation

Marina Espinosa, McParland, Emily, Serrano, Jayleann, et al., "3D Analysis of Eye and Extraocular Muscle Dimensions in Vertebrates Via Digital Segmentation" (2024). Summer Research Symposium, The Leadership Alliance Digital Library. Brown Digital Repository. Brown University Library. https://repository.library.brown.edu/studio/item/bdr:mf8v8unv/

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Summer Research Symposium

Each year, Brown University showcases the research of its undergraduates at the Summer Research Symposium. More than half of the student-researchers are UTRA recipients, while others receive funding from a variety of Brown-administered and national programs and fellowships and go …
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The Leadership Alliance Digital Library

A collection of research presentations and posters created by students participating in the Leadership Alliance's Summer Research - Early Identification Program.
When using this resource, please cite the digital object identifier (DOI) for the specific resource as well as the …

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3D Analysis of Eye and Extraocular Muscle Dimensions in Vertebrates Via Digital Segmentation