Sigma receptors are a unique pharmacologically defined class of drug-binding proteins comprised of the sigma-1 and sigma-2 subtypes. These subtypes are differentiated by their pharmacological …
Bacterial biofilms underlie the recalcitrance of many harmful infections to antibiotic treatment. One strategy that allows biofilms to evade antibiotics is the presence of a …
Expansion of trinucleotide repeat (TNR) DNA is implicated in several neurodegenerative disorders, including Huntington's Disease (HD). Expansion propensity and disease progression is dictated by repeat …
Exposure of human skin to solar ultraviolet radiation (UVR), a powerful carcinogen comprising ~95% UVA wavelengths (320-400 nm) and 5% UVB wavelengths (280-320 nm) at …
Cardiac myocytes (CM) and fibroblasts (CF) are the two major cell types in the heart. Overall, cardiac remodeling occurs in response to stress on the …