Antimicrobial resistance poses a global challenge to human health that is only expected to increase without significant treatment innovations. Novel therapeutic strategies are needed for …
Objective: There are 240 million cases of malaria each year, making it one of the most endemic diseases in modern history. However, not substantial preventative …
Synthesis and degradation of the extracellular matrix (ECM) are important for tissue development, morphogenesis, repair, and remodeling. Multiple proteinases are involved in the degradation of …
The androgen receptor (AR) signaling pathway plays a primary role in prostate cancer progression. Various types of second generation, non-steroidal anti-androgens (NSAA) including enzalutamide and …
Pulmonary fibrosis is a chronic and progressive interstitial lung disease, characterized by irreversible extracellular matrix (ECM) accumulation in the lungs, eventually leading to acute respiratory …
Neutrophils are the most abundant circulating white blood cell in the human body and the first responders to tissue injury and infection. While inflammation has …
Alzheimer’s is a debilitating neurodegenerative disease that results in memory loss, difficulty with language and learning, and overall impairments in everyday life. Currently, there is …
Introduction: Epstein-Barr virus (EBV) chronically infects most of the world’s population and due to its oncogenic nature, underlies approximately 1% of all cancers, including endemic …
JC polyomavirus (JCPyV) is a small non-enveloped virus that establishes lifelong, persistent infections in the majority of the adult population. Immune-competent patients are generally asymptomatic, …
As the release of novel chemicals into the environment outpaces the ability to perform exhaustive toxicological assessments, there is growing concern about the effects of …