Biomedical Engineering Theses and Dissertations

Theses and Dissertations for the Biomedical Engineering department.

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Description:: The central nervous system (CNS) contains a complex assortment of cell types and extracellular matrix proteins, which are arranged into an intricate architecture and ultimately …
Year:: 2016
Contributor:: Boutin, Molly E (creator); Hoffman-Kim, Diane (Director); Morgan, Jeffrey (Reader); Morrow, Eric (Reader); Franck, Christian (Reader); Vaccarino, Flora (Reader); Brown University. Biomedical Engineering (sponsor)
Genre:: theses
Subject:: optical clearing; three-dimensional culture; self-assembled spheroids; vasculogenesis; in vitro; Neurosciences; Tissue engineering; Fertilization in vitro
Language:: English
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Description:: Tendon and ligament injuries display poor healing capacities from the formation of scar-like tissue resulting in decreased mechanical properties. The application of biomechanics, the study …
Year:: 2024
Contributor:: Shaffer, Abigail (creator); Morgan, Jeffrey (Advisor); Horrigan, Diana (Reader); Gray, Marissa (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Biomedical engineering; Biomechanics; tissue engineering; Fibroblasts; microtissue; Cell culture; Ligaments; 3D Cell Culture; in vitro; tensile testing; tensile properties; uterosacral ligament; Connective tissues
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Description:: Objective: Traumatic brain injury (TBI) results when external forces exert strain on the brain, resulting in cell death, inflammation, and long-term neurological effects. To screen …
Year:: 2025
Contributor:: Vecchio, Francesca B (creator); Hoffman-Kim, Diane (Advisor); Kesari, Haneesh (Reader); Mayoral, Sonia (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Biomechanics; traumatic brain injury; high strain-rate deformation; 3D Cell Culture; in vitro; Rat Cortical Microtissues; 3d Bioprinting
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Description:: Scaffold-free, self-assembled, in vitro tissues hold promise for disease modeling and connective tissue engineering, but their mechanical characterization has been limited to static measures. Energy …
Year:: 2026
Contributor:: Nocevski, Nicholas (creator); Morgan, Jeffrey (Advisor); Srivastava, Vikas (Reader); Mathiowitz, Edith (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Biomedical engineering; Collagen; Viscoelasticity; Materials science; Bioengineering; Fibrosis; Constitutive Modeling; Computational modeling; in vitro; anisotropic materials; Connective tissues; Durability; 3D in vitro models; Collagen, SHG, Fiber Organization, Biomedical Engineering, Fluid Mechanics; 3D tissue engineering
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Description:: Abstract of Profiling Cancer Cell Invasion and Plasticity in Biomimetic Materials, by Amanda S. Khoo, Ph.D., Brown University, February 2022 Cancer metastasis is a major …
Year:: 2022
Contributor:: Khoo, Amanda S (creator); Wong, Ian (Advisor); Shukla, Anita (Reader); Reichner, Jonathan (Reader); Brodksy, Alexander (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Cancer; biomimetic model; Biomimetic materials; Cancer--Research; in vitro; Phenotypic plasticity; silk; collagen I; collagen VII
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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