The central nervous system (CNS) contains a complex assortment of cell types and extracellular matrix proteins, which are arranged into an intricate architecture and ultimately …
Our research works to 1)understand protective mechanisms for improving sunscreens through the study of ultra violet light absorbers and 2) develop a novel detection and …
All disciplines of biomedical research utilize in vitro models to answer a range of biological questions. Traditional in vitro models, two-dimensional (2D) cell monolayers, fail …
Aging is associated with an increased risk of arrhythmias and sudden cardiac death (SCD). Yet, much remains unknown about the mechanisms that underlie the age-related, …
Background: Older adults are increasingly spending more of their income on housing, which is associated with reduced spending on health care. This study tests the …
Background: Among patients with knee osteoarthritis (OA), total knee replacement (TKR) surgery is an important treatment option discussed between patient and provider. Previous studies have …
In this thesis,alpha-bungarotoxin (Bgtx) was validated as a tool for exploring the function and regulation of three otherwise Bgtx-insensitive ion channels: the first is a …
Eosinophilic esophagitis (EoE) is a chronic disease thought to manifest in response to exposure to antigens that induce eosinophil infiltration of the esophagus. Due to …
Background: For some patients with severe, treatment-resistant obsessive-compulsive disorder (OCD), neurosurgical interventions may be considered. While a few studies have assessed both patient and provider …
The mammalian forelimb is primarily used for locomotion. In bats, the arm, forearm, and hand anatomy are adapted to support flight by forming a wing, …
Anterior cruciate ligament (ACL) disruption is a common injury, particularly in the young and active patient. ACL reconstruction surgery is the current standard of care, …
Sex determination is an essential, and highly variable process, of organismal development. Looking for common threads used in evolution to determine sex is difficult simply …
As a versatile joint, the wrist remains stable through large motions under a variety of loading conditions. Wrist motion is achieved through the individual articulations …
BACKGROUND: There is a steady decline in the general surgery workforce in rural areas of the United States. In response, some surgery residency programs have …
Background: There is a steady decline in the general surgery workforce in rural areas of the United States. In response, some surgery residency programs have …
Wearable health monitors represent an essential area of research in biomedical engineering, where strain sensors play a major role in enabling effective and continuous health …
BACKGROUND: Screening, Brief Intervention, and Referral to Treatment (SBIRT) is an evidence-based method to identify, reduce, and prevent the harmful use of alcohol and illicit …
An exceptional group of aquatic invertebrates makes up Class Bdelloidea. Bdelloid rotifers are the only group of ancient asexual animals known. A second distinction that …
Although breast cancer screening assays exist, many are inaccessible, uninformative, and have high turnaround times, leaving a significant need for better alternatives. Here, we propose …