Dried blood spots technology has emerged as an attractive alternative to conventional venous blood sampling in both research and clinical settings due to its low …
The goal of this thesis was to use non-invasive quantifiable MR parameters of volume, signal intensity and T2* relaxation time to predict the biomechanical or …
Bone anchored prosthetic attachments, like other percutaneous devices, suffer from poor soft tissue integration, seen as chronic inflammation, infection, epithelial downgrowth and regression. We looked …
The central nervous system (CNS) contains a complex assortment of cell types and extracellular matrix proteins, which are arranged into an intricate architecture and ultimately …
Our research works to 1)understand protective mechanisms for improving sunscreens through the study of ultra violet light absorbers and 2) develop a novel detection and …
As a versatile joint, the wrist remains stable through large motions under a variety of loading conditions. Wrist motion is achieved through the individual articulations …
Understanding the fundamental mechanisms, and forces, underlying cell migration holds the promise of effective approaches for treating diseases and promoting cellular transplantation. One such disease …
Currently used titanium implants in orthopedics have a limited lifespan of only 15-20 years. The inadequate ability of the titanium implant to remain bonded to …
Traumatic injury to the spinal cord often results in irreversible loss of function as the central nervous system fails to spontaneously regenerate. The application of …
Nanoparticles are ubiquitous in a variety of fields, including pharmaceuticals, energy materials, composite materials, etc. As new nanoparticles are developed it becomes vital to understand …
Echolocating mammals such as bats, dolphins, and toothed whales perceive images of objects with hyper-resolution and navigate seamlessly through obstacles in complex acoustic environments. The …
Today bone defects such as bone fractures, osteoporosis or bone cancers represent a common and significant clinical problem. However, traditional micron size implant materials have …
This dissertation discusses two related clinical applications of visible regime diffuse reflectance spectroscopy as well as two new configurations of liquid crystal microspectrometer suitable in …
Growth factors are recognized as a vital component in the biological repair process, and the strategies developed for in situ tissue engineering and regenerative medicine …
Percutaneous implants are a family of devices that penetrate the skin and suffer from infection-mediated device failure caused by lack of integration/adhesion at the skin/device …
This dissertation focuses on the development of new drug delivery platforms using carbon nanotubes. Two nanotube systems, namely single walled carbon nanotubes (SWNTs) and multi-walled …
Desirable cytocompatibility properties of nano-sized ceramics were combined with the tunable degradability and deformability of a select polymer (poly-lactide-co-glycolide, or PLGA) to optimize biological and …
Titanium, titanium alloys, and cobalt-chromium alloys are widely used in orthopedic applications. To promote the osseointegration of implants into juxtaposed bone, an electrochemical surface modification …
