Transposable elements (TEs) are potentially harmful DNA sequences that can copy themselves and then insert elsewhere into the genome, causing damage and disrupting normal gene …
High Grade Serous Carcinoma (HGSC) is the deadliest form of ovarian cancer among women and causes the most deaths of gynaecological cancers overall (Tudrej, Patrycja …
SLC13A5 (mIndy, Hindy) encodes a Na+-coupled citrate transporter expressed on the plasma membrane of liver, testes, and brain tissue. SLC13A5 has been identified as a …
Human Immunodeficiency Virus (HIV) remains a global public health challenge, primarily due to its uncontrolled transmission. Analysis of HIV-1 sequence data can lead to phylogenetic …
Worldwide, 253 million people are afflicted with visual impairment. The development of novel therapies for the prevention and treatment of visual disorders is necessary 1. …
Transposable elements (TEs) are genetic elements that can move around the genome, causing mutations and genomic instability. These "jumping" genes are ubiquitous in the genomes …
Senescent cells have many harmful effects to the tissue they surround by creating an inflammatory environment and increase DNA damage by inducing retrotransposable elements. With …
Retrotransposable element (RTE) mobilization due to heterochromatin loss is among the molecular mechanisms associated with deleterious phenotypes that accompany biological aging. Here, we describe novel …
It has been known that early embryos are largely dependent on the Warburg Effect – a glycolysis-dependent metabolism – for energy. Yet, recent studies in …
Preterm birth disparately impacts different groups of women based on a number of risk factors. Nearly half of the risk is attributed to genetic factors. …
Cell-cell communication is crucial for the function of an organism. In Drosophila, motor neurons signal from the ventral nerve cord (VNC) to muscles while surrounding …
As the Earth’s climate is rapidly changing, it has become increasingly important to understand how to improve agricultural output, crop productivity, and crop viability. By …
Mfd is a transcriptional-repair coupling factor (TRCF) that is involved in a variety of cellular processes involving stalled or paused RNA polymerases, such as transcription …
RNA localization in Xenopus laevis oocytes is facilitated by the formation of specific cytoplasmic ribonucleoprotein (RNP) granules termed L-bodies. RNP granules, also known as biomolecular …
The need for tissues and organs presents a complex problem for our society that can be potentially resolved through bioengineering. Thus, there is an extensive …
Neurodegenerative diseases are a group of etiologically heterogeneous diseases characterized by the loss of a vulnerable subset of neurons. Despite this heterogeneity in etiology, TDP-43 …
In male Drosophila, the Dosage Compensation Complex (DCC) is targeted, via a transcription factor (TF), called the Chromatin-linked Adaptor for MSL complex (CLAMP), to the …
Premature infants, born before 37 weeks of gestation, need respiratory supports including mechanical ventilation and supplementary oxygen to maintain life. While ventilators and oxygen supplementation …
Among cancers that affect the female reproductive system, ovarian cancer exhibits the highest mortality rate, with a stark five-year survival rate for those having late-stage …
